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Therapy Herbal Untuk Nyeri Tulang

Sabtu, 15 Desember 2007

Nyeri, ngilu dan kekakuan gerak yang sering kita asumsikan sebagai rematik dan encok sebenarnya merupakan radang persendian (osteo-arthritis). Hal ini terjadi karena terbentuknya asam dalam otot dan menurunnya fungsi sistem pembuangan sehingga terjadi penumpukan sisa asam pada otot dan persendian kita. Selain hal itu, persendian juga menjadi tempat mengendapnya toksin-toksin.
Keadaaan demikian yang berlarut-larut akan dapat menyebabkan kelainan pada bentuk persendian. Banyak faktor dari kehidupan modern yang memperburuk kondisi penderita radang persendian. Kurangnya olah raga yang teratur, konsumsi yang berlebihan terhadap makanan gorengan (fast food), makanan yang berkadar gula tinggi (manis), daging merah (steak) dan lain-lain akan menghasilkan penumpukan asam laktat yang umumnya dikenal asam urat.
AV MBJ dengan 2 tahapan dasarnya, yakni : Cleansing (pembersihan) dan Rejuvenate (rejuvenasi-peremajaan sel) diformulasikan untuk menetralisir tumpukan sisa asam dan toksin-toksin pada persendian, selanjutnya membantu proses pembuangannya dengan memperbaiki / melancarkan sirkulasi darah sehingga akan mengurangi bahkan menghilangkan peradangan sendi secara lembut dan aman.
Dari hasil riset AV MBJ terbukti sangat efektif dalam menstimulasi sistem kekebalan tubuh. Dalam referensi imiah dikatakan bahwa arthritis merupakan masalah menurunnya sistem kekebalan tubuh. Oleh karena itu AV MBJ sangatlah efektif dan aman untuk perawatan dalam kasus-kasus arthritis mulai dari yang ringan sampai yang kronis.


Osteoarthritis (OS-tee-oh-are-THRY-tis) (OA), or degenerative joint disease, is one of the oldest and most common types of arthritis. It is characterized by the breakdown of the joint's cartilage. Cartilage is the part of the joint that cushions the ends of bones. Cartilage breakdown causes bones to rub against each other, causing pain and loss of movement. Most commonly affecting middle-aged and older people, OA can range from very mild to very severe. It affects hands and weight-bearing joints such as knees, hips, feet and the back.
The other common form of arthritis is Rheumatoid arthritis (RA) involves inflammation of the lining of many different joints in your body. In some people, RA can also affect other parts of the body, including the blood, the lungs, and the heart. Inflammation of the joint lining, called the synovium, can cause pain, stiffness, swelling, warmth, and redness. The affected joint may also lose its shape, resulting in loss of normal movement. RA can last a long time, and can be a disease of flares (active) and remissions (little to no activity. Arthritis is caused by an immune system disorder commonly referred to autoimmune disorder. It is characterized by chronic inflammation of joints, immobility of joints, chronic pain and water retention. Conventional therapies used in the treatment of arthritis are only palliative and offer no cure. Ayurveda recognizes the root cause of Arthritis and has been successfully used in the treatment of various forms of arthritis for centuries. Causes:
Abnormal wear and tear of connective tissues
Use of steroids and other muscle building drugs
Autoimmune disorder
Allergies
Lack of exercise
Composition
Boswellia serrata: Boswellia serrata tree is commonly found in India. The therapeutic value of its gum (sallaki) has been known. It posses good anti-inflammatory, anti-arthritic and analgesic activity. A randomized double blind placebo controlled crossover study was conducted to assess the efficacy, safety and tolerability of Boswellia serrata Extract (BSE) in 30 patients of osteoarthritis of knee, 15 each receiving active drug or placebo for eight weeks. After the first intervention, washout was given and then the groups were crossed over to receive the opposite intervention for eight weeks. All patients receiving drug treatment reported decrease in knee pain, increased knee flexion and increased walking distance. The frequency of swelling in the knee joint was decreased. Radiologically there was no change. The observed differences between drug treated and placebo being statistically significant, are clinically relevant. BSE was well tolerated by the subjects except for minor gastrointestinal ADRs. BSE is recommended in the patients of osteoarthritis of the knee with possible therapeutic use in other arthritis. In a separate study the researchers showed that compounds from the gum with genuine antiinflammatory effects are pentacyclic triterpenes of the boswellic acid type. Boswellic acids inhibit the leukotriene biosynthesis in neutrophilic granulocytes by a non-redox, noncompetitive inhibition of 5-lipoxygenase. The effect is triggered by boswellic acids binding to the enzyme. Moreover certain boswellic acids have been described to inhibit elastase in leukocytes, to inhibit proliferation, induce apoptosis and to inhibit topoisomerases of leukoma- and glioma cell lines. A series of chronic inflammatory diseases are thought to be perpetuated by leukotrienes. In clinical trials promising results were observed in patients with rheumatoid arthritis, chronic colitis, ulcerative colitis, Crohn's disease, bronchial asthma und peritumoral brains edemas. Commiphora mukul: One of the ingredients most commonly found in Ayurvedic arthritis formulas is guggul, an oleoresin of the herb Commiphora mukul (CM). The authors have conducted both preclinical and clinical investigations of guggul for reduction of pain, stiffness, and improved function, and to determine tolerability in older patients with a diagnosis of OA of the knee. METHODS: The study was conducted using an outcome, quasi-experimental, model. Thirty male and female participants meeting the inclusion/exclusion criteria, with a score of 2 or more on the Kellegran-Lawrence scale for at least 1 knee, were admitted in the study. CM was administered in capsule form (500 mg concentrated exact delivered TID) along with food. The WOMAC Total Score was used as a primary outcome measure. VAS scales, 6-minute walk-test, and WOMAC subscales were used as outcome measures. RESULTS: At the end of treatment, there was a significant difference in the scores of the primary and secondary outcome measures. On the primary measure, WOMAC total score, participants were significantly improved (P <>Cyprus scariosus: It is a pestiferous perennial weed with dark green glabrous culms, arising from a system of underground tubers. The plant has an elaborate underground system consisting of tubers, rhizomes and roots. The tubers are white and succulent when young, and hard and black when mature. Cyperine is the major constituent in the plant. The plant is a reputed hypotensive, anti-inflammatory & diuretic. Zingiber officinalis: Ginger, the rhizome of Zingiber officinale Roscoe (Zingiberaceae), is a commom constituent of diet worldwide and it has been reported that its extracts present some pharmacological activities. Here the researchers investigated the effects of the extract of ginger rhizomes on the classical models of rat paw and skin edema. The carrageenan-, compound 48/80- or serotonin-induced rat paw edema were inhibited significantly by the intraperitoneal administration of ginger extract. Ginger extract was also effective in inhibiting 48/80-induced rat skin edema at doses of 0.6 and 1.8 mg/site. Rat skin edema induced by substance P or bradikinin was not affected by treatment with Z. officinalis extract. The intraperitoneal administration of ginger extract (186 mg/kg(-1) body wt.) 1 hr. prior to serotonin injections, reduced significantly the serotonin-induced rat skin edema. Our results demonstrated that crude extract of Zingiber officinale was able to reduce rat paw and skin edema induced by carrageenan, 48/80 compound and serotonin. The antiedematogenic activity seems to be related, at least partially, to an antagonism of the serotonin receptor. In a separate study conducted at the Miami Veterans Affairs Medical Center and University of Miami, Florida, USA, 261 patients with OA of the knee and moderate-to-severe pain were enrolled in a randomized, double-blind, placebo-controlled, multicenter, parallel-group, 6-week study. After washout, patients received ginger extract or placebo twice daily, with acetaminophen allowed as rescue medication. The primary efficacy variable was the proportion of responders experiencing a reduction in "knee pain on standing," using an intent-to-treat analysis. A responder was defined by a reduction in pain of > or = 15 mm on a visual analog scale. RESULTS: In the 247 evaluable patients, the percentage of responders experiencing a reduction in knee pain on standing was superior in the ginger extract group compared with the control group (63% versus 50%; P = 0.048). Analysis of the secondary efficacy variables revealed a consistently greater response in the ginger extract group compared with the control group, when analyzing mean values: reduction in knee pain on standing (24.5 mm versus 16.4 mm; P = 0.005), reduction in knee pain after walking 50 feet (15.1 mm versus 8.7 mm; P = 0.016), and reduction in the Western Ontario and McMaster Universities osteoarthritis composite index (12.9 mm versus 9.0 mm; P = 0.087). Change in global status and reduction in intake of rescue medication were numerically greater in the ginger extract group. Change in quality of life was equal in the 2 groups. Patients receiving ginger extract experienced more gastrointestinal (GI) adverse events than did the placebo group (59 patients versus 21 patients). GI adverse events were mostly mild.

1 komentar:

  1. maria mengatakan...

    berap lamakah proses penyembuhan penyakit hmp?
    berap harga obat AV MBJ?
    Dimanakah bisa mendapatkan obat tersebut?

    4 Maret 2010 23.43  

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